From Genes to Genomes: Concepts and Applications of DNA Technology. Author (s): Analysis of Genetic Variation (Pages: ). In sports, “going back to the basics” is an often-heard cliché, used when sophisticated maneuvers fail to win games. In current biomedical research, where many. accounts potentially include selectively neutral traits spread by genetic drift'', It is necessary for the completion of a causal analysis to ask for any feature.
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and is not intended for resale, dissemination, or duplication. Genetics: Analysis of Genes and Genomes, Ninth Edition. Includes Navigate 2 Advantage Access. tions of DNA fingerprinting and the diagnosis of human genetic disorders. In for genome-wide analysis of gene structure and expression, including com-. The Genetics of Bacteria and Viruses. Chapter 9. Genetic Engineering and Genome Analysis. Chapter Gene Expression. Chapter
Genes to Genomics will fill the gap, cover much of the same ground as previous titles, but go further on contemporary topics like transgenics, sequence comparison and analysis of variation. The authors, Daniel L. Chapter 12 covers some of the most recent studies in genomics, proteomics, and transgenics. Chapters 6 through 8 provide an in-depth description of the molecular biology of DNA replication and recombination, chromosome organization, human karyotypes, and chromosomal behavior. For example, the mutation of P21 and Bax genes is rather rare, and although their protein products do inhibit cell proliferation and promote apoptosis, respectively, it may be a stretch to lump them into the category of tumor suppressor gene. Analysis of Genes and Genomes is an outstanding textbook, and I would not hesitate to recommend it to anyone at any stage of his or her academic or research career. The University of Texas M.
Over recent years these topics have filtered down the curriculum and are currently taught as core topics at second year, with a corresponding change in textbook requirements.
Where once second year students were restricted to learning about the concept and theory of gene cloning, now they routinely clone genes for themselves as part of their practical assignments.
Genes to Genomics will fill the gap, cover much of the same ground as previous titles, but go further on contemporary topics like transgenics, sequence comparison and analysis of variation. It will also include the illustrations and images from the textbook, in addition to worked examples, answers to questions within the book, and links to related websites of key interest.
Reviews "This monograph is excellently organized….
This book would be an outstanding addition to the library of an undergraduate or graduate student and a useful aid for the libraries of mentors of undergraduate studies. Free Access.
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New Password. Hartl and Elizabeth W. Jones, are well-established geneticists and educators.
Their simple and reader-friendly writing style and beautifully done graphs make the book a great read and even make some difficult concepts easy to understand.
In this edition, Hartl and Jones adeptly integrate classic transmission genetics with molecular genetics and modern genomics. This material is inspiring, and I could not help going through many of the stories in my mind and then sharing some with my graduate students and even senior researchers.
This is indeed one of the best textbooks I have read, and it should be a must-have genetics book not only for college and graduate students but also for biomedical researchers who are working on human diseases, including cancer, that have a genetic and molecular basis. The book is divided into 18 chapters that guide the reader through the diverse topics that make up modern genetics.
Chapter 1 is an overview of genetics and introduces the basic concepts of molecular genetics. In Chapters 3 through 5, the authors focus on transmission genetics, chromosome and sex-chromosome inheritance, genetic linkage, and chromosome mapping.
Chapters 6 through 8 provide an in-depth description of the molecular biology of DNA replication and recombination, chromosome organization, human karyotypes, and chromosomal behavior. Chapter 9 is devoted to the genetics of bacteria and their viruses. Chapters 10 and 11 cover gene expression and gene regulation. Chapter 12 covers some of the most recent studies in genomics, proteomics, and transgenics. Although this is the chapter that focuses on genomics, much important information learned from the Human Genome Project is provided throughout the book whenever appropriate.
For example, in a table on page in chapter 10 showing the characteristics of human transcripts, the source is a Lander paper published in reporting the results from the Human Genome Project. In Chapter 15, which is about the cell cycle, a transcriptome profile of yeast genes during different phases of the cell cycle is shown.
Chapter 13 deals with the genetic control of development in animals and plants as well as important experimental systems such as the nematode and Drosophila.
Chapters 14 and 15 discuss the molecular mechanisms of gene mutation, DNA repair, the cell cycle, and cancer. Chapter 16, which focuses on mitochondrial DNA and extranuclear inheritance, should also be of great interest to cancer researchers, although this chapter does not consider the role of mitochondria in cancer. Chapter 17 is on molecular evolution and population genetics. As the last chapter of the book, Chapter 18 provides readers with a dose of reality, focusing on the genetic basis of complex traits and inheritance.
The book contains much practical information for effective communication. The authors also teach scientific approaches to discovery, in some cases with a touch of humor.
The publishers also maintain a feature called GeNETics on their Web page to provide additional Internet-based resources for inquisitive readers who want to explore various topics further.
Overall this is an outstanding book.