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Mrtechnicolor marked it as to-read Jul 24, Mr A Dhanani rated it really liked it Aug 26, Books by Martin Bland. Get A Copy. Error rating book.
It includes the design of clinical trials and epidemiological studies, data collection, summarizing and presenting data, probability, standard error, confidence intervals and significance tests, techniques of data analysis including multifactorial methods and the choice of statistical method, problems of medical measurement and diagnosis, vital statistics, and calculation of sample size.
The new edition describes the design and analysis of medical research studies in a clear and user friendly manner.
The third edition includes new topics such as consent in clinical trials, design and analysis of cluster-randomized trials, ecological studies, conditional probability, repeated testing, random effects models, intraclass correlation and conditional odds ratios.
Material which is encountered only at the postgraduate level has been indicated clearly in the text to facilitate ease or use.
The book is firmly grounded in medical data, particularly in medical research, and includes real illustrative examples. There are multiple choice questions and 17 long questions involving calculations to which fully explained solutions are provided. This new book of questions and answers includes no calculations and is complementary to the exercises given here.
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Excellent book and definitely more than an introduction to medical statistics. First time I read this book was during my Pediatric Hematology Oncology fellowship, and since then I can't stop referring my friends to this book. If you would take this during a practical course ,I would rate it 5 stars. Highly recommended! Db rated it liked it Jul 19, Dylan rated it liked it Feb 07, Joachim Ahlbeck rated it really liked it Sep 18, Lee Baker rated it it was amazing Jan 31, Emma Shore rated it really liked it Apr 18, John Campbell rated it it was amazing Jan 29, Mr A Dhanani rated it really liked it Aug 26, Bean Gepner rated it it was ok Aug 30, Edma rated it liked it Jul 18, Lana Hakobyan rated it really liked it Sep 27, Stephen Corson rated it it was amazing Apr 14, Michael rated it it was amazing Dec 14, Mark rated it it was amazing Sep 26, Coco rated it it was amazing Aug 17, Robbie added it Feb 18, Cindy added it Sep 16, Nivedita is currently reading it Aug 08, Toryn Green added it Oct 21, Heather Walker added it Jan 29, Mrtechnicolor marked it as to-read Jul 24, Una ricerca clinica che prevede un controllo si dice controllata.
Sottoponendo a trattamento un gruppo di pazienti insensibili al placebo, si ha la sicurezza che gli effetti del trattamento siano veramente attribuibili ad esso. Manca tuttavia un confronto con un altro farmaco attivo. Le ricerche controllate si dividono in eterocontrollate tra individui diversi ed autocontrollate entro gli stessi individui.
Si dispone di una casistica e la si suddivide in tanti gruppi quanti sono i trattamenti mediante scelta casuale. Costituisce un'ottima scelta nel caso in cui si disponga di due parti simmetriche di pazienti, da attribuire, mediante randomizzazione, all'uno o all'altro trattamento.
Viene realizzata somministrando trattamento e controllo allo stesso paziente, alternandoli mediante randomizzazione. Ha il difetto di essere possibile solo per trattamenti che non forniscono risultati permanenti; richiede inoltre un periodo di sospensione tra i due cicli di somministrazione. Ha il pregio di non raddoppiare i pazienti, ma il difetto di raddoppiare il tempo di prova.
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